CA-125/CEA ratio as a prognostic factor in type II endometrial cancer: a single institute experience

Autor: İ. Karadağ, S. Karakaya, Ö. Ateş, Ö. Çakmak Öksüzoğlu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: World Cancer Research Journal, Vol 9 (2022)
Druh dokumentu: article
ISSN: 2372-3416
DOI: 10.32113/wcrj_202212_2453
Popis: Objective: Type II (non-endometrioid) endometrial cancer is less common with an incidence of 10%-20%. It has an aggressive clinical course with heterogeneous clinic pathological features. The aim of this study is to evaluate prognostic factors and survival outcomes in type II endometrial cancer. Patients and Methods: Patients aged over 18 years with diagnosis of Stage IA-IVB type II endometrial cancer were included to the study. Between 2013 and 2019, a total of 76 patients were evaluated retrospectively. Results: Median overall survival (OS) was 25 months while median disease-free survival (DFS) was 22 months. Median DFS was 25 months (95% CI: 14.71-35.28) in patients with negative lymph nodes while it was 10 months (95% CI: 6.88-13.11) in patients with positive lymph nodes (p=0.017). Median OS was 28 months (95% CI: 23.05-32.95) in patients with a ratio of CA-125/CEA
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