The nature of excessive sleepiness and sudden sleep onset in Parkinson׳s disease

Autor: Daniel Gurgel Fernandes Távora, Veralice Meireles Sales de Bruin, Romulo Lopes Gama, Emily Mourão Soares Lopes, Iago Farias Jorge, Pedro Felipe Carvalhedo de Bruin
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Sleep Science, Vol 7, Iss 1, Pp 13-18 (2014)
Druh dokumentu: article
ISSN: 1984-0063
DOI: 10.1016/j.slsci.2014.07.020
Popis: Objectives: Excessive daytime sleepiness (EDS) and sudden sleep onset (SOS) episodes are frequent in Parkinson׳s disease (PD). The objectives are to identify clinical characteristics and factors associated with EDS and SOS episodes. Methods: Clinical demographic data were recorded (N=100, mean age=65.0±10.4). EDS was identified by the Epworth Sleepiness Scale (ESS>10) and SOS episodes were registered. Disease severity was evaluated by the Unified Parkinson׳s Disease Rating Scale (UPDRS, I, II, and III), sleep disturbances by the Parkinson׳s Disease Sleep Scale (PDSS10) and rapid eye movement (REM) sleep behavior disorder (RBD) by the REM sleep behavior scale. Levodopa equivalent dose was measured. Results: PD patients with EDS (67%) were predominately male (73.1%) and had worse disease severity (UPDRS II and III p= 0.005); SOS episodes (39%) were associated with disease duration, diabetes, sleep disturbances (PDSS Scale), disease severity (UPDRS I, II, III) and RBD symptoms (p
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