Long-term Changes in the Premature Death Rate in Lung Cancer in a Developed Region of China: Population-based Study

Autor: Wenjing Ye, Weiwei Lu, Xiaopan Li, Yichen Chen, Lin Wang, Guangwang Zeng, Cheng Xu, Chen Ji, Yuyang Cai, Ling Yang, Zheng Luo
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JMIR Public Health and Surveillance, Vol 8, Iss 4, p e33633 (2022)
Druh dokumentu: article
ISSN: 2369-2960
DOI: 10.2196/33633
Popis: BackgroundLung cancer is a leading cause of death worldwide, and its incidence shows an upward trend. A study of the long-term changes in the premature death rate in lung cancer in a developed region of China has great exploratory significance to further clarify the effectiveness of intervention measures. ObjectiveThis study examined long-term changes in premature lung cancer death rates in order to understand the changes in mortality and to design future prevention plans in Pudong New Area (PNA), Shanghai, China. MethodsCancer death data were collected from the Mortality Registration System of PNA. We analyzed the crude mortality rate (CMR), age-standardized mortality rate by Segi’s world standard population (ASMRW), and years of life lost (YLL) of patients with lung cancer from 1973 to 2019. Temporal trends in the CMR, ASMRW, and YLL rate were calculated by joinpoint regression expressed as an average annual percentage change (AAPC) with the corresponding 95% CI. ResultsAll registered permanent residents in PNA (80,543,137 person-years) from 1973 to 2019 were enrolled in this study. There were 42,229 deaths from lung cancer. The CMR and ASMRW were 52.43/105 and 27.79/105 person-years, respectively. The YLL due to premature death from lung cancer was 481779.14 years, and the YLL rate was 598.16/105 person-years. The CMR and YLL rate showed significantly increasing trends in men, women, and the total population (P
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