Endothelial Function and Oxidative Stress in X-Linked, gp91phox Deficiency, Chronic Granulomatous Disease

Autor: Yukihito Higashi, MD, PhD, Shinji Kishimoto, MD, PhD, Tatsuya Maruhashi, MD, PhD
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: JACC: Case Reports, Vol 2, Iss 10, Pp 1480-1483 (2020)
Druh dokumentu: article
ISSN: 2666-0849
DOI: 10.1016/j.jaccas.2020.05.086
Popis: Two patients with X-linked chronic granulomatous disease without NAPDH oxidase activity and with high responses of flow-mediated vasodilation are reported. Bone marrow transplantation restored oxidative stress to the levels of those in healthy subjects and decreased flow-mediated vasodilation to the levels of those in healthy subjects in both of the patients. (Level of Difficulty: Advanced.)
Databáze: Directory of Open Access Journals