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Objective To investigate the nutritional status of hematopoietic stem-cell transplantation patients and the construction and application of nutritional management scheme. Methods This study adopts a prospective research method, taking 120 patients with hematopoietic stem-cell transplantation treated in our hospital from January 2020 to September 2021 as the research objects. Patients were randomly divided into observation group and control group. The patients in the control group take routine nursing guidance, and the patients in the observation group take nutrition intervention mode nursing under team management, Both groups were intervened for 2 weeks. The differences of influencing factors, physiological indexes, immune indexes and prognosis between the two groups were compared. Results After treatment, Hb, ALB, PAB, TP, IBW %, MAMC, complement C3, complement C4, IgA, IgG and IgM in the two groups were significantly increased, and Hb, ALB, PAB, TP, IBW %, MAMC, complement C3, complement C4, IgA, IgG and IgM in the observation group were significantly higher than those in the control group(P＜0. 05). The incidence of malnutrition, acute graft-versus-host disease and infection during transplantation in the observation group were significantly lower than those in the control group(P＜0. 05). Conclusion The nutritional intervention under the team management mode adopted by patients with stem cell transplantation has significantly improved their nutritional and immune indexes. (目的 探讨造血干细胞移植患者营养情况及营养管理方案的构建与应用效果。方法 采取前瞻性研究方法, 选取2020年1月—9月在本院进行治疗的120例造血干细胞移植术患者作为研究对象, 随机分为观察组及对照组, 各60例。对照组患者采取常规营养指导, 观察组患者采取团队管理下的营养干预模式护理。两组患者均干预2周。比较两组患者的影响因素、生理指标、免疫指标、预后之间的差异。结果 经过治疗后, 两组患者的血红蛋白(HB)、白蛋白(ALB)、前蛋白(PAB)、总蛋白(TP)、实际体质量与理想体质量的比值(IBW%)、上臀中部肌围(MAMC)、补体C3、补体C4、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)均显著升高, 且观察组患者的HB、ALB、PAB、TP、IBW%、MAMC、补体C3、补体C4、IgA、IgG、IgM显著高于对照组(P＜0. 05)。观察组患者的营养不良发生率、急性移植物抗宿主病发生率、移植期感染率显著低于对照组(P＜0. 05)。结论 给予造血干细胞移植患者团队管理模式下的营养干预, 能有效营养指标以及免疫指标显著改善。) |
