Survival analysis of surgical versus nonsurgical treatment in stage I to III small cell lung cancer in the last 20 years: A systematic review and meta‐analysis

Autor:	Zhijian Liang, Xiaoqi Li, Xiao Li
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	nonsurgical treatment meta‐analysis small cell lung cancer surgical treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Thoracic Cancer, Vol 14, Iss 25, Pp 2525-2535 (2023)
Druh dokumentu:	article
ISSN:	1759-7714 1759-7706
DOI:	10.1111/1759-7714.15062
Popis:	Abstract More and more patients with small cell lung cancer (SCLC) have received surgical treatment in the last 20 years. This meta‐analysis compared whether surgical treatment can bring greater survival benefits to patients with stage I–III SCLC compared with chemotherapy, radiotherapy and chemoradiotherapy. Pubmed, Embase, Web of Science, Cochrane library database, and ClinicalTrials were searched for relevant articles. The main outcomes were overall survival (OS), reported as hazard ratios (HRs), and 95% confidence intervals (CIs). A total of 19 articles containing 30 185 patients (3940 patients receiving surgical treatment and 26 245 patients receiving nonsurgical treatment) were included in this study. Surgical resection significantly improved OS when compared to nonsurgical treatment in retrospective studies (HR: 0.55, 95% CI: 0.47–0.64, p
Databáze:	Directory of Open Access Journals
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