| Autor: |
Eva Imelda, Khairan Khairan, Rodiah R. Lubis, Pati Kemala, Utari Zulfiani, Suci Rahayu, Ghazi M. Idroes, Sarra M. Adev, Nur B. Maulydia, Rinaldi Idroes |
| Jazyk: |
English<br />Spanish; Castilian |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Journal of Pharmacy & Pharmacognosy Research, Vol 11, Iss 5, Pp 833-840 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
0719-4250 |
| DOI: |
10.56499/jppres23.1691_11.5.833 |
| Popis: |
Context: In Aceh, Hippobroma longiflora, known as kitolodby the locals, is believed to possess medicinal benefits such as anticataract. Aims: To investigate the anticataract activity of ethanolic extract from H. longiflora leaves ex vivo. Methods: The dried fine powder of H. longiflora was macerated using ethanol at room temperature, and the concentrated extract was prepared in concentrations ranging from 100 to 300 μg/mL. The cataract model was established by using goat lens induced with H2O2 and later exposed to the extract for treatment. Anti-cataract activity was assessed by observing the change in lens opacity. Further, malondialdehyde levels and activities of endogenous antioxidants (superoxide dismutase, glutathione peroxidase, and catalase). Results: The apparent cataract opacity reduced after the exposure of the extract was observed macroscopically. The cataract eyes experienced a significant increase (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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