Low-dose aspirin in the prevention of pre-eclampsia in China: postpartum hemorrhage in subgroups of women according to their characteristics and potential bleeding risk

Autor: Jiahui Chen, Jing Huai, Li Lin, Boya Li, Yuchun Zhu, Huixia Yang, Yanjie Yin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Chinese Medical Journal, Vol 136, Iss 5, Pp 550-555 (2023)
Druh dokumentu: article
ISSN: 0366-6999
2542-5641
00000000
DOI: 10.1097/CM9.0000000000002545
Popis: Abstract. Background:. The APPEC study is a large-population randomized controlled trial in China evaluating the role of low-dose aspirin prophylactic treatment for pre-eclampsia. There was no statistically significant difference in postpartum hemorrhage (PPH) incidence between the aspirin and control groups. This study aimed to evaluate the potential bleeding risk of 100 mg aspirin in high-risk pregnant women and the difference in the incidence of PPH according to maternal characteristics. Methods:. This is a secondary data analysis of the APPEC study. Platelet counts and coagulation test results were collected at five follow-up visits. Subgroups defined by maternal age (
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