The physiological determinants of near-infrared spectroscopy-derived regional cerebral oxygenation in critically ill adults

Autor: Michael D. Wood, Jill A. Jacobson, David M. Maslove, John G. Muscedere, J. Gordon Boyd, The Cerebral Oxygenation and Neurological Outcomes Following Critical Illness (CONFOCAL) Research Group
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-15 (2019)
Druh dokumentu: article
ISSN: 2197-425X
DOI: 10.1186/s40635-019-0247-0
Popis: Abstract Background To maintain adequate oxygen delivery to tissue, resuscitation of critically ill patients is guided by assessing surrogate markers of perfusion. As there is no direct indicator of cerebral perfusion used in routine critical care, identifying an accurate strategy to monitor brain perfusion is paramount. Near-infrared spectroscopy (NIRS) is a non-invasive technique to quantify regional cerebral oxygenation (rSO2) that has been used for decades during cardiac surgery which has led to targeted algorithms to optimize rSO2 being developed. However, these targeted algorithms do not exist during critical care, as the physiological determinants of rSO2 during critical illness remain poorly understood. Materials and methods This prospective observational study was an exploratory analysis of a nested cohort of patients within the CONFOCAL study (NCT02344043) who received high-fidelity vital sign monitoring. Adult patients (≥ 18 years) admitted
Databáze: Directory of Open Access Journals
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