Characterizing and Modulating Brain Circuitry through Transcranial Magnetic Stimulation Combined with Electroencephalography

Autor: Faranak Farzan, Marine Vernet, Mouhsin Shafi, Alexander Rotenberg, Zafiris Jeff Daskalakis, Alvaro Pascual-Leone
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Frontiers in Neural Circuits, Vol 10 (2016)
Druh dokumentu: article
ISSN: 1662-5110
DOI: 10.3389/fncir.2016.00073
Popis: The concurrent combination of transcranial magnetic stimulation (TMS) with electroencephalography (TMS-EEG) is a powerful technology for characterizing and modulating brain networks across developmental, behavioral and disease states. Given the global initiatives in mapping the human brain, recognition of the utility of this technique is growing across neuroscience disciplines. Importantly, TMS-EEG offers translational biomarkers that can be applied in health and disease, across the lifespan, and in humans and animals, bridging the gap between animal models and human studies. However, to utilize the full potential of TMS-EEG methodology, standardization of TMS-EEG study protocols is needed. In this article, we review the principles of TMS-EEG methodology, factors impacting TMS-EEG outcome measures, and the techniques for preventing and correcting artifacts in TMS-EEG data. To promote the standardization of this technique, we provide comprehensive guides for designing TMS-EEG studies and conducting TMS-EEG experiments. We conclude by reviewing the application of TMS-EEG in basic, cognitive and clinical neurosciences, and evaluate the potential of this emerging technology in brain research.
Databáze: Directory of Open Access Journals