Mesoporous biophotonic carbon spheres with tunable curvature for intelligent drug delivery

Autor: Fu Jianye, Hui Tiankun, An Dong, Shan Wei, Chen Guobo, Wageh Swelm, Al-Hartomy Omar A., Zhang Bin, Xie Ni, Nie Guohui, Jiao Jinqing, Qiu Meng, Zhang Han
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nanophotonics, Vol 11, Iss 22, Pp 5165-5175 (2022)
Druh dokumentu: article
ISSN: 2192-8606
2192-8614
DOI: 10.1515/nanoph-2022-0523
Popis: Mesoporous carbon spheres (MCSs) are widely used in the field of pollutants adsorption, energy storage and various biomedicine applications such as targeted delivery vector, phototherapy sensitizers, bioimaging contrast agents, etc. Current synthetic strategies including soft templating and hard templating methods generally have the limits of using expensive surfactants or lack of control over the pore structures. Therefore, the complex and uncontrollable pore structures limit its further clinical application. Herein, we proposed a new synthetic strategy to control the uniformity of pore channel arrangement in MCSs which can modulate the photonic property and the corresponding light controlled drug release property in intelligent drug delivery. The as obtained MCSs with relative uniform pore channel arrangement and long pore channels are demonstrated to have the best NIR light-induced drug release performance. This work provides not only new synthetic method to modulate pore structure characteristics and biophotonic property of MCSs, but also uniform MCSs as novel delivery platforms with advanced controlled release performance.
Databáze: Directory of Open Access Journals