| Autor: |
Noriyoshi Masuoka, Kulwadee Tamsampaoloet, Warinthorn Chavasiri, Isao Kubo |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Heliyon, Vol 2, Iss 9 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2405-8440 |
| DOI: |
10.1016/j.heliyon.2016.e00169 |
| Popis: |
Anacardic acid C15:3 and cardol C15:3 sigmoidally suppressed superoxide anion (O2-) generation using xanthine oxidase. To study this suppression activity, anacardic acids, cardanols and cardols having different numbers of double bonds in alk(en)yl chains were prepared. The O2- scavenging activity and H2O2 formation from O2- using PMS-NADH were examined. Anacardic acids and cardols indicated sigmoidal O2- scavenging activity but cardanols did not. The O2- scavenging activity of anacardic acid C15:3 was weaker than the suppression activity using xanthine oxidase, but the scavenging activity of cardol C15:3 was quite similar to the suppression using xanthine oxidase. The H2O2 formation from O2- decreased by the addition of anacardic acids, cardanols and cardols but increased by the addition of gallic and caffeic acids. From these results, we deduced that the O2- suppression activity of xanthine oxidase reaction with cardols is the O2- scavenging activity and that anacardic acids and cardols are O2- scavengers having low prooxidant property. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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