Coronary artery ectasia: prevalence, angiographic characteristics and clinical outcome

Autor: Nadav Asher Willner, Scott Ehrenberg, Anees Musallam, Ariel Roguin
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Open Heart, Vol 7, Iss 1 (2020)
Druh dokumentu: article
ISSN: 2053-3624
DOI: 10.1136/openhrt-2019-001096
Popis: ObjectiveDetermine coronary artery ectasia (CAE) prevalence and clinical outcome in a large cohort of patients underwent coronary angiography.MethodsIn an 11-year period, between 2006 and 2017, 20 455 coronary angiography studies were performed at a large university centre. Patients diagnosed with CAE based on procedure report were included in the final analysis.ResultsCAE was diagnosed in 174 out of 20 455 studies (0.85% per total angiograms, 161 patients). Patients’ average age was 59.6±11.2 years old with male predominance (90.7%). Diffuse ectasia morphology was most common (78.9%), followed by fusiform (16.1%) and saccular (5%). Mixed CAE and atherosclerotic heart disease (ASHD) was present in 75.2% of the patients and isolated CAE in 24.8%. The most common coronary artery involved was the right coronary artery (RCA) (79%). Following index angiography, all the isolated CAE group was managed conservatively, while 67% of the mixed CAE-ASHD group underwent coronary intervention. In an average follow-up of 6±3.6 years, adverse clinical event (a composite endpoint of any death, cerebrovascular accident, myocardial infarction, thromboembolic event, bleeding and stent thrombosis) occurred in 48.8% of the mixed CAE-ASHD group compared with 25% in the isolated CAE group (p
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