Insights into Androgen Receptor Action in Lung Cancer

Autor:	Darko Durovski, Milica Jankovic, Stefan Prekovic
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	androgens nuclear receptors lung cancer Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Endocrines, Vol 4, Iss 2, Pp 269-280 (2023)
Druh dokumentu:	article
ISSN:	2673-396X
DOI:	10.3390/endocrines4020022
Popis:	Sex hormones and their receptors play a crucial role in human sexual dimorphism and have been traditionally associated with hormone-dependent cancers like breast, prostate, and endometrial cancer. However, recent research has broadened our understanding by revealing connections with other types of cancers, such as lung cancer, where the androgen receptor has been found to be particularly significant. This review aims to explore the molecular mechanisms of androgen action in lung cancer pathogenesis and progression, highlighting the potential of inhibiting the androgen receptor signaling pathway as a therapeutic strategy for lung cancer treatment.
Databáze:	Directory of Open Access Journals
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