| Autor: |
Beier, Justus P., Boos, Anja M., Weigand, Annika, Arkudas, Andreas, Horch, Raymund E. |
| Jazyk: |
German<br />English |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
GMS German Plastic, Reconstructive and Aesthetic Surgery – Burn and Hand Surgery, Vol 5, p Doc05 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2193-7052 |
| DOI: |
10.3205/gpras000033 |
| Popis: |
Engineering functional skeletal muscle tissue still remains a major challenge. So far clinically relevant sizes of functional skeletal muscle tissue could not be engineered yet. One of the obstacles to overcome is the development of a suitable scaffold for muscle tissue engineering in vivo, another is the lack of differentiation in expanded adult muscle precursor cells. Materials and different architectures of scaffolds which are used for engineering functional skeletal muscle are presented here as well as approaches to the differentiation challenge. Finally the translation from cell culture over small to large animal models for engineering axially vascularized musculoskeletal tissues will be described. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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