| Autor: |
Wang-Yong Yang, Rui Gao, Mark Southern, Partha S. Sarkar, Matthew D. Disney |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms11647 |
| Popis: |
Expanded RNA repeats in non-coding region of a gene represent a hallmark of several diseases. Here, the authors identify two small molecules that selectively bind AU repeats and use them to design a compound that targets the pathogenic RNA associated with spinocerebellar ataxia type 10. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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