Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study

Autor:	Omer Toprak, Huseyin Kurt, Yasin Sarı, Cihat Şarkış, Halil Us, Ali Kırık
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Chronic kidney disease Hypomagnesemia Obesity Insulin resistance Pre-diabetes Dermatology RL1-803 Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the genitourinary system. Urology RC870-923
Zdroj:	Kidney & Blood Pressure Research, Vol 42, Iss 1, Pp 33-42 (2017)
Druh dokumentu:	article
ISSN:	1420-4096 1423-0143
DOI:	10.1159/000468530
Popis:	Background/Aims: Magnesium is an essential mineral for many metabolic functions. There is very little information on the effect of magnesium supplementation on metabolic profiles of chronic kidney disease (CKD) patients. The aim of this study was to assess the influence of magnesium supplementation on metabolic profiles of pre-diabetic, obese and mild-to-moderate CKD patients with hypomagnesemia. Methods: A total of 128 hypomagnesemic, pre-diabetic and obese patients with an estimated glomerular filtration rate between 90 and 30 ml/min/1.73m2 were enrolled in a randomised, double-blind, placebo-controlled trial. Patients in the magnesium group received 365 mg of oral magnesium (n = 57) once daily for 3 months, while patients in the control group received a placebo (n = 61), also once daily for 3 months. Hypomagnesemia is defined by a serum magnesium level
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f56447f2b9a94a9ca0d47adf74c6645e Zobrazit plný text záznamu View record in DOAJ