| Autor: |
Niccolò Castellino, Antonio Longo, Andrea Russo, Vincenza Bonfiglio, Matteo Fallico, Mario Damiano Toro, Francesco Cappellani, Marco Grillo, Agostino Gaudio, Lorenzo Lo Cicero, Concetto Sessa, Michele Colaci, Lorenzo Malatino, Pietro Castellino, Teresio Avitabile, Luca Zanoli |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Medicine, Vol 11 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2296-858X |
| DOI: |
10.3389/fmed.2024.1294432 |
| Popis: |
ObjectivesTo assess the reversibility of retinal microvascular changes in the long term and to investigate the potential links with other vascular diseases of COVID-19.MethodsWe designed a prospective multicenter observational study. Patients were enrolled from the Methuselah study cohort. Retinal vascular function was studied in these patients using optical coherence tomography angiography (OCTA); aortic stiffness was measured using aortic pulse wave velocity. These examinations were performed 1 (Visit 1) and 12 (Visit 2) months after the hospital discharge for severe COVID-19. A control subject group matched for age and sex was included to define normal values.ResultsA total of 28 control subjects (56 eyes) and 25 patients (50 eyes) completed the scheduled OCTA assessment; 18 patients (36 eyes) also completed the macrovascular examination. Compared to controls, the vessel density of the superficial capillary plexus (SCP) was reduced, whereas the foveal avascular zone area was enlarged at Visit 1 (p = 0.016 and |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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