Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.

Autor: Luís Fábio da Silva Batista, Vânia Lúcia Ribeiro da Matta, Thaise Yumie Tomokane, Acácio Duarte Pacheco, Fernando Tobias Silveira, Claudio Nazaretian Rossi, Mary Marcondes, Márcia Dalastra Laurenti
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 49, Iss 3, Pp 361-364 (2016)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-0360-2015
Popis: Abstract: INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. RESULTS Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. CONCLUSIONS Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas.
Databáze: Directory of Open Access Journals