| Autor: |
Wei-Chun Chen, Huei-Jean Huang, Lan-Yan Yang, Yu-Bin Pan, Kuan-Gen Huang, Cheng-Tao Lin, Min-Yu Chen, Yun-Hsin Tang, Ting-Chang Chang, Chyong-Huey Lai, Hung-Hsueh Chou |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Biomedical Journal, Vol 45, Iss 5, Pp 821-827 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2319-4170 |
| DOI: |
10.1016/j.bj.2021.10.003 |
| Popis: |
Background: To investigate outcomes and morbidity of patients undergoing secondary cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in recurrent ovarian cancer. Materials and methods: Between April 2014 and January 2019, a total of 51 recurrent ovarian cancer patients receiving secondary CRS and HIPEC were retrospectively reviewed. Results: Among the 51 patients, median peritoneal cancer index score was 13 (range 3–34), and completeness of cytoreduction (CC) score of 0/1 was achieved in 41 patients (78.8%). Regimen of HIPEC included cisplatin and paclitaxel in 39 (75%) cases. The median follow-up duration of survivors was 20.2 months. Sixteen (30.8%) patients remained free of recurrence after HIPEC. The median progression-free survival (PFS) and overall survival (OS) were 11.8 months and 34.5 months respectively. Multivariate analysis showed previous chemotherapy |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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