| Autor: |
Parizad Mohammadnejad, Seyed Mohamadreza Milani Hosseini, Beheshteh Sohrabi |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Sensors and Actuators Reports, Vol 7, Iss , Pp 100187- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2666-0539 |
| DOI: |
10.1016/j.snr.2024.100187 |
| Popis: |
In aqueous solution, a non-toxic fluorescent nanosensor incorporating graphene quantum dots encased in molecularly imprinted polymer (GQDs-encased in MIP) is manufactured through a straightforward sol-gel process. During the polymerization process, the functional monomer 3-aminopropyltriethoxysilane (APTES) and the cross-linker tetraethyl orthosilicate (TEOS) were utilized to bind the biotin in a polymer network. The resulting GQDs@MIP nanocomposite outperformed the similar non-imprinted polymer (GQDs-encased in NIP) in terms of biotin selectivity. Under ideal conditions, the produced GQD-encased in MIP are employed to detect biotin by quenching their fluorescence caused by the target analyte via photo induced electron transfer (PET). The quenching curves of each GQDs-encased in polymer were fitted with the Stern-Volmer-type equation, and GQDs-encased in MIP had a broader linear range and a lower limit of detection than GQDs-encased in NIP. GQDs-encased in MIP fluorescence response is linear with respect to biotin concentration over a wide linear range of at least 0.4 μmol L − 1 to 6.7 μmol L − 1. The detection limit for biotin determination was 315 nmol L − 1. The suggested GQDs-encased in MIP is promising for the measurement of trace biotin in human serum samples because to its non-toxicity, simplicity, and low cost, as well as its strong analytical performance. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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