| Autor: |
A. F. Novikova, D. Yu. Konstantinov, A. A. Suzdaltsev, A. F. Verbovoj, O. V. Kosareva |
| Jazyk: |
ruština |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Журнал инфектологии, Vol 10, Iss 2, Pp 98-102 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2072-6732 |
| DOI: |
10.22625/2072-6732-2018-10-2-98-102 |
| Popis: |
The purpose of the research is to determine the value of adiponectin levels in patients chronic hepatitis C with metabolic syndrome depending on the severity of fibrosis and histological activity in the liver.Materials and methods. The research included 72 patients chronic hepatitis C with metabolic syndrome. All patients underwent calculation of body mass index, determination of adiponectin level in serum. The stage of liver fibrosis and degree of histological activity was determined according to METAVIR scale based on histological research of biopsy specimens obtained at liver biopsy. The average age in the research group amounted to 40,73±6,3 years. Prevailed patients with a body mass index of 26–30 kg/m² – 61,1%. All patients had abdominal obesity, the gender differences in the prevalence of abdominal obesity was not found. In 73.6% of cases, it was patients with moderate or severe liver fibrosis; 44,4% – moderate-severe and severe degree of histological activity. The mean value of adiponectin is made up 9,36±3,28 microgram /ml. Was an inverse relationship between body weight and adiponectin level. The patients chronic hepatitis C with metabolic syndrome found a significant reduction in levels of adiponectin, compared with healthy people. In women were observed significantly lower adiponectin levels compared to men (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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