An Easy-to-Implement Risk Score for Targeted Hepatitis C Virus Testing in the General Population

Autor: Javier Martínez-Sanz, María Jesús Vivancos-Gallego, Borja Manuel Fernández-Felix, Alfonso Muriel, Pilar Pérez-Elías, Almudena Uranga, Beatriz Romero, Juan Carlos Galán, Santiago Moreno, María Jesús Pérez-Elías
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Microbiology Spectrum, Vol 10, Iss 2 (2022)
Druh dokumentu: article
ISSN: 2165-0497
DOI: 10.1128/spectrum.02286-21
Popis: ABSTRACT Despite the effectiveness of available treatments, hepatitis C virus (HCV) remains a major public health problem, mainly due to the high percentage of undiagnosed individuals. We aim to create an easy-to-implement risk score to facilitate targeted HCV testing in the general population. This is a substudy derived from a prospective study in primary care in Madrid (Spain). Participants completed a 21-question risk assessment questionnaire, followed by HCV testing for those with at least one positive response and those >50 years of age, even if they did not answer positively. We used the population >50 years of age to fit a logistic regression model to create a score predicting the risk of a positive test result. We then performed a sensitivity analysis by applying the score obtained to the population
Databáze: Directory of Open Access Journals