Is arterial stiffness in HIV-infected individuals associated with HIV-related factors?
| Autor: | P. Monteiro, D.B. Miranda-Filho, F. Bandeira, H.R. Lacerda, H. Chaves, M.F.P.M. Albuquerque, U.R. Montarroyos, R.A.A. Ximenes |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 45, Iss 9, Pp 818-826 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0100-879X 1414-431X |
| Popis: | We investigated the association between pulse wave velocity (PWV) and HIV infection, antiretroviral treatment-related characteristics, viral load, immune status, and metabolic changes in a cross-sectional study nested in a cohort of HIV/AIDS patients who have been followed for metabolic and cardiovascular changes since 2007. The study included patients recruited from the cohort (N = 261) and a comparison group (N = 82) of uninfected individuals, all enrolled from April to November 2009. Aortic stiffness was estimated using the carotid-femoral PWV (Complior-Artech, Paris, France). The groups were similar with respect to age, metabolic syndrome, diabetes mellitus, Framingham score, and use of antihypertensive and hypolipidemic medications. Hypertension was more frequent among the controls. Individuals with HIV had higher triglyceride, glucose and HDL cholesterol levels. Among individuals with HIV/AIDS, those with a nadir CD4+ T-cell count |
| Databáze: | Directory of Open Access Journals |
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