Does the Pattern of Endometrium Influence the Frozen Embryo Transfer Cycle Outcome?

Autor: Monna Pandurangi, N Sanjeeva Reddy, G Usha Rani, Hepzibha Kirubamani, V Radha, N Siddhartha
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 15, Iss 11, Pp 12-15 (2021)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2021/51476.15684
Popis: Introduction: Implantation rates vary between 25-35% despite all advancements in Assisted Reproductive Technology (ART). Successful implantation requires embryo endometrial synchrony. Transvaginal Ultrasonography (TVS) plays an essential role in assessing endometrial receptivity. Aim: To study the influence of different echo patterns of the endometrium in predicting the outcome of Frozen Embryo Transfer (FET) cycle. Materials and Methods: A prospective observational study was performed to determine the effect of endometrial pattern on the outcomes of FET cycles. A total of 348 women who underwent endometrial preparation for FET from January 2012 to December 2017 were included. On the day of starting progesterone, the study participants were divided into three groups based on the endometrial pattern: Type A: Triple line or multilayer pattern; Type B: Isoechoic pattern; and Type C: Hyperechoic pattern.The association of endometrial pattern with the outcomes of FET cycles- pregnancy rate (primary end point), clinical pregnancy and live birth rate (secondary outcome), were determined. Statistical analysis was performed using Statistical Package for the Social Sciences (SPSS) version 23.0 software using paired student’s t-test, Chi-square test, Fisher’s-exact test, Analysis of Variance (ANOVA) and logistic regression. A probability value of
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