| Autor: |
Chakiri Radia, Gallouj Salim, Inani Kawtar, Mernissi Fatima Zahra, Harmouch Taoufiq |
| Jazyk: |
English<br />Spanish; Castilian<br />French<br />Polish |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nasza Dermatologia Online, Vol 8, Iss 2, Pp 128-132 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2081-9390 |
| DOI: |
10.7241/ourd.20172.36 |
| Popis: |
Introduction: Pemphigoid gestationis (PG) is a rare autoimmune skin disorder that occurs during pregnancy. Materials and Methods: Prospective study including all cases of PG diagnosed between 2010 and 2015. Results: We reported 16 patients: 12 multiparous and 4 primiparous, the average age was 30.43 years. The onset of the disease was done in 43.75% of cases at 3 trimester, and 25% of the 2 trimester with three cases of early post partum and post abortum cases. All patients had urticarial papules, vesicule were found in 85.7%. The beginning was done in periumbilical 62.5%. Histology objectified in all cases a sub epidermal detachment, and the IFD performed in 8 cases, objectified in 6 patients a linear deposit of C3 along the dermoepidermal junction. All patients were treated with Bethametasone at 30 g/d with a progressive degression over several months. Concerning the fetal prognosis we found two cases of prematurity, and one case of fetal death. One patient had a choriocarcinoma complicated molar pregnancy. Conclusion: All our patients evolved well under topical corticosteroids of very strong class, even with extensive lesions, so suggesting their first-line use, avoiding the recourse to the oral corticotherapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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