Use of the CytoSorb adsorber in patients with acute-on-chronic liver failure

Autor: Patrick Haselwanter, Bernhard Scheiner, Lorenz Balcar, Georg Semmler, Marlene Riedl-Wewalka, Monika Schmid, Thomas Reiberger, Christian Zauner, Mathias Schneeweiss-Gleixner
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-61658-3
Popis: Abstract CytoSorb is a hemoadsorptive column used to remove high concentrations of proinflammatory cytokines in septic shock. Data on CytoSorb application in acute-on-chronic liver failure (ACLF) is lacking. This retrospective observational study analyzed 21 ACLF patients admitted to ICUs at the Vienna General Hospital who received CytoSorb adsorber therapy between 2017 and 2023. Median ICU length of stay was 8 days (IQR: 3–13), the ICU survival rate was 23.8% (n = 5). Significant decreases in bilirubin (median peak: 20.7 mg/dL to median post-treatment: 10.8 mg/dL; − 47.8%; p
Databáze: Directory of Open Access Journals
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