Effects of respiratory muscle training on parasympathetic activity in diabetes mellitus
| Autor: | C.S.C. Trevisan, A.S. Garcia-Araújo, A.C.G.O. Duarte, V.O. Furino, T.L. Russo, A. Fujimoto, H.C.D. Souza, R.B. Jaenisch, R. Arena, A. Borghi-Silva |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 54, Iss 7 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1414-431X 1414-431x |
| DOI: | 10.1590/1414-431x2020e10865 |
| Popis: | This study verified the effects of respiratory muscle training (RMT) on hemodynamics, heart rate (HR) variability, and muscle morphology in rats with streptozotocin-induced diabetes mellitus (DM). Thirty-six male Wistar rats were randomized into 4 groups and 34 completed the study: i) sham-sedentary (Sham-ST; n=9); ii) sham-RMT (Sham-RMT; n=9); iii) DM-sedentary (DM-ST; n=8); and iv) DM-RMT (DM-RMT; n=8). Hemodynamics were assessed by central cannulation, and R-R intervals were measured by electrocardiogram. In addition, the effects of RMT on the cross-sectional area of the diaphragm, anterior tibial, and soleus muscles were analyzed. The induction of DM by streptozotocin resulted in weight loss, hyperglycemia, reduced blood pressure, and attenuated left ventricular contraction and relaxation (P |
| Databáze: | Directory of Open Access Journals |
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