| Autor: |
Antonia Calvo-Cano, Eugenio Garduño-Eseverri, Ana Alastruey-Izquierdo, Román Hernández-Gallego, Rocío Martínez-Gallardo, Francisco Félix Rodríguez-Vidigal |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Medical Mycology Case Reports, Vol 30, Iss , Pp 35-38 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2211-7539 |
| DOI: |
10.1016/j.mmcr.2020.10.001 |
| Popis: |
Invasive aspergillosis (IA) is associated with a high mortality rate in kidney-transplant recipients. Azole-resistance is increasing in Aspergillus fumigatus. We report a clinical case of a kidney-transplant recipient with cerebellar and pulmonary aspergillosis caused by azole-resistant Aspergillus parafelis (molecular identification through β-tubulin sequence). The patient experienced an effective resolution after three surgical procedures and associated antifungal therapy. This case highlights that azole-resistant aspergillosis should be considered in every patient with IA as long as susceptibility testing results are not known. Therefore, in selected patients with IA and central nervous system involvement, empirical combination antifungal therapy could be considered. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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