| Autor: |
Damian Krzyzanowski, Aleksandra Oszer, Joanna Madzio, Maciej Zdunek, Julia Kolodrubiec, Bartosz Urbanski, Wojciech Mlynarski, Szymon Janczar |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Frontiers in Immunology, Vol 14 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1664-3224 |
| DOI: |
10.3389/fimmu.2023.1128581 |
| Popis: |
Congenital defects of neutrophil number or function are associated with a severe infectious phenotype that may require intensive medical attention and interventions to be controlled. While the infectious complications in inherited neutrophil disorders are easily understood much less clear and explained are autoimmune and autoinflammatory phenomena. We survey the clinical burden of autoimmunity/autoinflammation in this setting, search for common patterns, discuss potential mechanisms and emerging treatments. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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