Interstitial nephritis: Two pediatric cases with atypical radiological features

Autor: Joseph Connors, BS, Rachel Aronov, Laura Malaga-Dieguez, MD, PhD, Suzanne Vento, RN, Laura Jane Pehrson, RN, Ming Wu, MD, Shailee Lala, MD, Howard Trachtman, MD
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Radiology Case Reports, Vol 13, Iss 5, Pp 1003-1006 (2018)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2018.07.011
Popis: Interstitial nephritis (IN) is a relatively rare entity in children and adolescents that can be caused by a range of disorders including infection, medications, inflammatory bowel disease, and sarcoid. There is no proven therapy for this condition. We present 2 cases of biopsy-proven interstitial nephritis, of which 1 case was with granulomatous features that presented with unusual sonographic findings of discrete mass lesions in the kidney parenchyma bilaterally. Although a precise cause could not be identified in either case, 1 patient progressed to end-stage kidney disease (ESKD) and the other is in the early stages of treatment. We suggest that recognition of the atypical imaging features of interstitial nephritis may enable early recognition of this condition and avoid confusion with neoplastic or infectious processes. Keywords: Interstitial nephritis, Granulomatous interstitial nephritis, Pediatric, Mass-like lesions, Sonography, Kidney biopsy
Databáze: Directory of Open Access Journals