Attitude and knowledge towards the effectiveness of nucleic acid-based vaccines among healthcare workers and medical students in the Jordanian population

Autor: M. Emad Al Madadha, Rama Rayyan, Khalid E. Ahmed, Nancy Al-Sanouri, Saddam Al Demour, Muayyad Ahmad
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Cogent Public Health, Vol 9, Iss 1 (2022)
Druh dokumentu: article
ISSN: 27707571
2770-7571
DOI: 10.1080/27707571.2022.2145756
Popis: AbstractSince the beginning of the COVID-19 pandemic, catastrophic mortality and morbidity rates and unknown long-term ramifications were caused, leading to focused efforts on implementing effective vaccination. Nucleic acid-based vaccines (NBVs), an emergent advance in vaccine development, presented high efficacy rates but controversy regarding this approach soon spread. This study assesses healthcare workers (HCWs) knowledge and attitude towards NBVs’ effectiveness. This cross-sectional study was conducted in Jordan from November 2020 to January 2021 through a web-based questionnaire. 320 participants were split into educated and uneducated groups, with the former being exposed to educational material on NBVs before survey completion. The educated group expressed increased concern towards NBVs’ side effects. Specifically, the risk of developing cancer due to genetic modification(40.8%), fever(69.4%), skin rash(58.0%), and amyloid deposition(40.8%) showed a significant difference. The educated group preferred RNA-based NBVs over DNA-based ones(43.9%), had double the response rate, provided more scientifically accurate answers, and showed a more positive attitude towards the ability of NBVs to induce cellular immunity (57.3%) and prevent chronic forms of COVID-19(57.3%) (p
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