Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China

Autor:	Fei He, Ren-dong Xiao, Tao Lin, Wei-min Xiong, Qiu-ping Xu, Xu Li, Zhi-qiang Liu, Bao-chang He, Zhi-jian Hu, Lin Cai
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Dietary patterns BCMO1 polymorphisms Primary lung cancer Chinese Case-control study Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-018-4361-2
Popis:	Abstract Background We investigated whether BCMO1 variants and dietary patterns are associated with lung cancer risk. Methods Case-control study including 1166 lung cancer cases and 1179 frequency matched controls was conducted for three BCMO1 variants (rs6564851, rs12934922, and rs7501331) and four dietary patterns were investigated. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs). Results The rs6564851, rs12934922, and rs7501331 were not found to be associated with lung cancer risk (P > 0.05). In multivariable-adjusted models, compared to the lowest quartile of the score on the “fruits and vegetables” pattern, the highest quintile was associated with a 78.4% decreased risk (OR Q4 vs. Q1 = 0.216; 95% CI, 0.164–0.284; P for trend
Databáze:	Directory of Open Access Journals
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