Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings

Autor: James S. Leathers, M. Belen Pisano, Viviana Re, Gertine van Oord, Amir Sultan, Andre Boonstra, Jose D. Debes
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Annals of Global Health, Vol 85, Iss 1 (2019)
Druh dokumentu: article
ISSN: 2214-9996
DOI: 10.5334/aogh.2562
Popis: Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.
Databáze: Directory of Open Access Journals