Folate-receptor 1 level in periodontal disease: a pilot study

Autor: Duygu Alkan, Berrak Guven, Cigdem Coskun Turer, Umut Balli, Murat Can
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Oral Health, Vol 19, Iss 1, Pp 1-5 (2019)
Druh dokumentu: article
ISSN: 1472-6831
DOI: 10.1186/s12903-019-0909-z
Popis: Abstract Background The purpose of this study was to investigate gingival crevicular fluid (GCF) and serum folate-receptor 1 (FOLR1) levels in subjects with different periodontal status. Methods The study consists of three groups: Healthy group (n = 15), gingivitis group (n = 15) and chronic periodontitis group (n = 15). Clinical periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), gingival index (GI) and bleeding on probing (BOP) were assessed. GCF and serum samples were collected from each patient and were analyzed FOLR1 levels by enzyme-linked immunosorbent assay. Results The values of FOLR1 in GCF were higher in gingivitis and periodontitis groups than among patient in control group (p
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