Elephantiasic Pretibial Myxedema: A Rare Manifestation in Graves’ Disease

Autor: Apichat Kaewdech, Kumpol Aiempanakit, Siripan Sangmala, Kanokphorn Chiratikarnwong, Sauvarat Auepemkiate, Josef Symon S. Concha
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Health Science and Medical Research (JHSMR), Vol 37, Iss 2, Pp 151-155 (2019)
Druh dokumentu: article
ISSN: 2586-9981
2630-0559
DOI: 10.31584/jhsmr.201942
Popis: Elephantiasic pretibial myxedema is an extremely rare condition, affecting patients with thyroid disease. The clinical manifestation is difficult to diagnosis, and the treatment is challenging. Herein, the authors report on a case of a patient with Graves’ disease, who had a long-standing enlargement of bilateral legs, and histopathologic studies confirmed the diagnosis as; pretibial myxedema. The patient was treated with an antithyroid drug, iodine-131 (131I) irradiation, a potent topical corticosteroid, with occlusion, and compression therapy, however, the patient’s skin condition remained unchanged. This report aims to demonstrate a rare form of pretibial myxedema, to review the clinical presentations, differential diagnosis as well as therapeutic options.
Databáze: Directory of Open Access Journals