Comparison the effect of movento, a chemical pesticide, with chitosan, a biologic pesticide, on female reproductive system in Balb/C mice
Autor: | Sakineh Kaboli Kafshgiri, Kazem Parivar, Javad Baharara, Nasim Hayati Roodbari, Mohammad Amin Kerachian |
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Jazyk: | English<br />Persian |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | یافتههای نوین در علوم زیستی, Vol 3, Iss 4, Pp 279-287 (2017) |
Druh dokumentu: | article |
ISSN: | 2423-6330 2476-7115 |
Popis: | Chemical pesticides possess toxic and destructive impacts on the reproductive system and disrupt endocrine function. In this experimental study, the effect of movento, as a chemical pesticide, was investigated in comparison with chitosan, a biological pesticide, on the female reproductive system in vivo. In this study, 56 mice were randomly dived into 7 groups including control and experimental groups treated with movento and chitosan. After a 21-day treatment, mice were killed and their ovaries and blood being collected. In addition, the samples were fixed and stained with H & E method. The results exhibited that treatment with 2.5 and 5 mg/kg chitosan had no significant effect on the number and diameter of primary, secondary and antral follicles, while these items were significantly reduced in 10 mg/kg ch-itosan group and all movento-treated groups as well. In addition, the level of sexual hormones, such as estradiol, FSH and LH, was decreased in 10 mg/kg chitosan group and all movento-treated groups in comparison with the control gr-oup. The findings showed that movento affected the sexual hormone levels, ovary and ovarian follicle structure and in-duced abnormality in female reproductive system, while chitosan, as a biological pesticide, should be used due to its minimum effects on female reproductive system |
Databáze: | Directory of Open Access Journals |
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