| Autor: |
Fang Wang, Chun Wang, Jie Wang, Yefang Zou, Xiaoxue Chen, Ting Liu, Yan Li, Yonglong Zhao, Yongjun Li, Bin He |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Royal Society Open Science, Vol 6, Iss 6 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2054-5703 |
| DOI: |
10.1098/rsos.190338 |
| Popis: |
HDAC inhibitors have been developed very rapidly in clinical trials and even in approvals for treating several cancers. However, there are few reported HDAC inhibitors designed from Nɛ-acetyl lysine. In the current study, we raised a novel design, which concerns Nɛ-acetyl lysine derivatives containing amide acetyl groups with the hybridization of ZBG groups as novel HDAC inhibitors. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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