Nanostructured Biomaterials with Controlled Properties Synthesis and Characterization

Autor: Petcu C, Somoghi Raluca, Teodor Eugenia, Liţescu SimonaCarmen, Mihalache Mihaela
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Nanoscale Research Letters, Vol 4, Iss 6, Pp 544-549 (2009)
Druh dokumentu: article
ISSN: 1931-7573
1556-276X
DOI: 10.1007/s11671-009-9278-x
Popis: Abstract Magnetic nanoparticles were obtained using an adjusted Massart method and were covered in a layer-by-layer technique with hydrogel-type biocompatible shells, from chitosan and hyaluronic acid. The synthesized nanocomposites were characterized using dynamic light scattering, transmission electron microscopy, and Fourier transformed infrared spectroscopy. Biocompatibility of magnetic nanostructures was determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) cell proliferation assay, swelling tests, and degradation tests. In addition, interaction of hydrogel-magnetic nanoparticles with microorganisms was studied. The possibility of precise nanoparticles size control, as long as the availability of bio-compatible covering, makes them suitable for biomedical applications.
Databáze: Directory of Open Access Journals
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