| Autor: |
Nahideh Nazdikbin Yamchi, Mohammad Mojtaba Alizadeh Ashrafi, Hamed Abbasi, Farhad Amjadi, Mohammad Hossein Geranmayeh, Reza Shirazi, Amin Tamadon, Reza Rahbarghazi, Mahdi Mahdipour |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-11 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2662-7671 |
| DOI: |
10.1186/s12906-022-03759-y |
| Popis: |
Abstract Background: The restorative effect of classical music was assessed on the cyclophosphamide-induced animal model of premature ovarian failure (POF). Methods: Mozart’s piano classical music (K.448) was used for up to 4 and 8 weeks. Rats were exposed to music 6 h every day using a stereo system with a volume of 65–70 dB. Sera and ovarian tissue samples were collected for the evaluation of FSH, LH, and E2 and histopathological examination. At the same time points, samples were taken from the hypothalamus and hippocampus to monitor the expression of Ntrk2, Crh, and Pomc using real-time PCR. Mating trial was performed to evaluate the fertility status of POF rats. Results: Histopathological examination revealed a significant increase (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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