Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in Caenorhabditis and Vertebrates

Autor: Diego A. Caraballo, Lucila I. Buzzi, Carlos P. Modenutti, Ana Acosta-Montalvo, Olga A. Castro, María S. Rossi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: G3: Genes, Genomes, Genetics, Vol 10, Iss 2, Pp 755-768 (2020)
Druh dokumentu: article
ISSN: 2160-1836
DOI: 10.1534/g3.119.400868
Popis: UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and Caenorhabditis genomes harbor two uggt gene copies that exhibit differences in their properties.
Databáze: Directory of Open Access Journals