The Effectiveness of Suffruticosol B in Treating Lung Cancer by the Laser Trapping Technique

Autor: Mulugeta S. Goangul, Rance M. Solomon, Daniel L. Devito, Charles A. Brown, James Coopper, Daniel B. Erenso, Ying Gao, Aline Pellizzaro, Jennifer M. Revalee, Horace T. Crogman
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biophysica, Vol 3, Iss 1, Pp 109-120 (2023)
Druh dokumentu: article
ISSN: 2673-4125
DOI: 10.3390/biophysica3010008
Popis: We used laser trapping to study the effects of suffruticosol B on lung cancer cells. Physical and mechanical changes were found to be statistically significant, with a 63.97% increase over untreated cells and a 79.57% increase over untreated cells after treatment for 3 or 6 h, respectively. The treatment affected the internal structure of the cells, with changes in their elastic properties. The cellular responses showed that treatment with suffruticosol B resulted in the decreased proliferation and invasion of cancer cells. These results suggest that the treatment may be useful in preventing or treating lung cancer.
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