Sequence-Based Identification of Metronidazole-Resistant Clostridioides difficile Isolates

Autor:	Wiep Klaas Smits, Céline Harmanus, Ingrid M.J.G. Sanders, Lynn Bry, Grace A. Blackwell, Quinten R. Ducarmon, Eliane de Oliveira Ferreira, Ed J Kuijper
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Clostridioides difficile Antimicrobial resistance bacteria enteric infections metronidazole plasmid Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 28, Iss 11, Pp 2308-2311 (2022)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2811.220615
Popis:	The plasmid pCD-METRO confers metronidazole resistance in Clostridioides difficile. We showed high sequence similarity among pCD-METRO plasmids from different isolates and identified pCD-METRO and associated metronidazole-resistant isolates in clinical and veterinary reservoirs in the Americas. We recommend using PCR or genomic assays to detect pCD-METRO in metronidazole-resistant C. difficile.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ef43e38d211640b491ce57be17b0a3fd Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF