Red Rice Bran Extract Intervention Ability to Improve Lipid Profile and Malondialdehyde Levels in Type 2 Diabetes Mellitus Model Rats

Autor: Isniati Dwijayanti, Brian Wasita, Ida Nurwati
Jazyk: English<br />Indonesian
Rok vydání: 2022
Předmět:
Zdroj: Amerta Nutrition, Vol 6, Iss 4, Pp 404-413 (2022)
Druh dokumentu: article
ISSN: 2580-1163
2580-9776
DOI: 10.20473/amnt.v7i4.2022.404-413
Popis: Background: Diabetes mellitus accompanied by oxidative stress can cause cardiovascular complications. Red rice bran extract contains antioxidants that have the potential to prevent oxidative stress and improve hyperlipidemia in patients with type 2 diabetes mellitus. Objectives: Analyzing the effect of red rice bran extract on lipid profile and malondialdehyde levels in a diabetes mellitus rat model. Methods: Pretest-Posttest Control Group Design. Thirty-five male Wistar Albino rats were divided into 5 groups, namely, negative control, positive control given acarbose as much as 1.8 mg/200gr/day, and 3 treatment groups given red rice bran extract, 165, 330, 660 mg/kg/day for 21 days, respectively. Results: There was a change in lipid profile and MDA levels (p
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