Clinical and Economic Benefit of Achieving Disease Control in Psoriatic Arthritis and Ankylosing Spondylitis: A Retrospective Analysis from the OM1 Registry

Autor: Martin J. Bergman, Patrick Zueger, Jayeshkumar Patel, Christopher D. Saffore, Ia Topuria, Cristi Cavanaugh, Siran Fang, Jerry Clewell, Alexis Ogdie
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Rheumatology and Therapy, Vol 10, Iss 1, Pp 187-199 (2022)
Druh dokumentu: article
ISSN: 2198-6576
2198-6584
DOI: 10.1007/s40744-022-00504-2
Popis: Abstract Background There is limited evidence on the clinical and economic benefit of achieving disease control in psoriatic arthritis (PsA) and ankylosing spondylitis (AS), thus we aimed to assess the impact of disease control on healthcare resource use (HCRU) and direct medical costs among US patients with PsA or AS over 1 year. Methods Data were derived from the US OM1 PsA/AS registries (PsA: 1/2013–12/2020; AS: 01/2013–4/2021) and the Optum Insight Clinformatics® Data Mart to identify adult patients with PsA or AS. Two cohorts were created: with disease control and without disease control. Disease control was defined as modified Disease Activity Index for Psoriatic Arthritis (DAPSA28) ≤ 4 for PsA and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
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