| Autor: |
Meshari Almutairi, Tariq Raina, Abdullah Alobaid |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Interdisciplinary Neurosurgery, Vol 26, Iss , Pp 101342- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2214-7519 |
| DOI: |
10.1016/j.inat.2021.101342 |
| Popis: |
Chiari malformations have long been considered sporadic conditions, without a heritable etiology. However, there have been a number of case reports identifying familial aggregation and clustering of Chiari malformation type 1, suggesting a genetic basis.The authors report a 53 years old mother and 32 years old daughter duo, who presented with symptomatic Chiari malformation type 1 suggesting familial transmission. A literature review was conducted and familial Chiari malformation type 1 has been increasingly reported, however, genetic data are still under investigation. Clinicians need to be aware of familial Chiari malformation type 1 that could help in early identification and intervention for family members at risk, allowing for improved patient outcome. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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