VE/VCO2 slope in lean and overweight women and its relationship to lean leg mass

Autor: Manda L. Keller-Ross, Daniel P. Chantigian, Nicholas Evanoff, Anne E. Bantle, Donald R. Dengel, Lisa S. Chow
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 21, Iss , Pp 107-110 (2018)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2018.10.009
Popis: Ventilation/carbon dioxide production (VE/VCO2slope) is used clinically to determine cardiorespiratory fitness and morbidity in heart failure (HF). Previously, we demonstrated that lower lean leg mass is associated with high VE/VCO2slope during exercise in HF. In healthy individuals, we evaluated 1) whether VE/VCO2slope differed between lean and overweight women and 2) the relationship between lean leg mass and VE/VCO2slope in overweight sedentary (OWS), overweight trained (OWTR) and lean, trained (LTR) women. Methods: Gas exchange and ventilation were collected during a treadmill peak oxygen uptake test (VO2peak) in 40 women [26 OWS (29 ± 7 yrs., mean ± SD), 7 OWTR (33 ± 5 yrs) and 7 LTR (26 ± 6 yrs)]. Body composition was measured by dual X-ray absorptiometry. Results: VO2peak was highest in LTR (46.6 ± 8 ml/kg/min) compared with OWTR (38.1 ± 4.9 ml/kg/min) and OWS women (25.3 ± 4.8 ml/kg/min, p 0.05). Higher lean leg mass was associated with lower VE/VCO2slope in overweight women (OWS + OWTR: r = −0.55, p
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