Cardiovascular risk assessment in type 2 diabetes mellitus: comparison of the World Health Organization/International Society of Hypertension risk prediction charts versus UK Prospective Diabetes Study risk engine
| Autor: | Herath HMM, Weerarathna TP, Umesha D |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Vascular Health and Risk Management, Vol 2015, Iss default, Pp 583-589 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1178-2048 41678168 |
| Popis: | Herath M Meththananda Herath, Thilak Priyantha Weerarathna, Dilini Umesha Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka Introduction: Patients with type 2 diabetes mellitus (T2DM) are at higher risk of developing cardiovascular diseases, and assessment of their cardiac risk is important for preventive strategies. Purpose: The Ministry of Health of Sri Lanka has recommended World Health Organization/International Society of Hypertension (WHO/ISH) charts for cardiac risk assessment in individuals with T2DM. However, the most suitable cardiac risk assessment tool for Sri Lankans with T2DM has not been studied. This study was designed to evaluate the performance of two cardiac risk assessments tools; WHO/ISH charts and UK Prospective Diabetes Study (UKPDS) risk engine. Methods: Cardiac risk assessments were done in 2,432 patients with T2DM attending a diabetes clinic in Southern Sri Lanka using the two risk assessment tools. Validity of two assessment tools was further assessed by their ability to recognize individuals with raised low-density lipoprotein (LDL) and raised diastolic blood pressure in a cohort of newly diagnosed T2DM patients (n=332). Results: WHO/ISH charts identified 78.4% of subjects as low cardiac risk whereas the UKPDS risk engine categorized 52.3% as low cardiac risk (P20%. Agreement between the two tools was poor (κ value =0.144, P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|