| Popis: |
Comparative tests on the removal of doxycycline hydrochloride, the tetracycline series antibiotic, from the body of broiler chickens using Belvetsorb and Ultrasorb enterosorbents after oral application for 5 days in a therapeutic and prophylactic dose were carried out. Already on the 4th day after cessation of antibiotic feeding was observed across more intense decreasing of the concentration of doxycycline in the meat of chickens treated with Belvetsorb food, Ultrasorb food and Ultrasorb with water (65.6 % to 80% and 81 %, respectively). This trend continued in the subsequent period after the end of the use of doxycycline hydrochloride (from 10 to 13 days). On the 14th day after stopping the drinking of doxycycline hydro-chloride, there was a significantly more intense decrease in the antibiotic content in the meat of chickens receiving Belvetsorb with feed, Ultrasorb with feed and especially, Ultrasorb with water (15.7%, 19.4% and 76.3%, respectively). Limit content in meat and meat products doxycycline should be less than 0.1 mg/kg. The tests identified the most rapid excretion of doxycycline when administered to chickens sorbent "Ultrasorb" method of feeding. The use of the sorbent "Ultrasorb" by the method of drinking leads to the content of residual amounts of doxycycline in the meat of broiler chickens to an acceptable level for 10 days after the end of antibiotic use, the use of Ultrasorb and Belvetsorb with feed – for 12 days and 13 days, respectively. In the control group without the use of drugs, the permissible level of doxycycline in broiler meat was achieved only on day 14. Thus, the use of these drugs and, first of all, Ultrasorb with water can be recommended to reduce the waiting period after the use of tetracycline antibiotics in poultry farming. Further research will be aimed at studying the effect of sorbents on reducing the waiting period after the use of other tetracycline antibiotics, as well as other classes of antibiotics that are removed from the body mainly unchanged with faeces and urine. |
