Designing ATHN 7: Safety, effectiveness and practice of treatment of people with haemophilia in the United States through a natural history cohort study

Autor: Buckner Tyler W., Daoud Nabil, Miles Moses, O'Neill Carrie, Watson Crystal, Recht Michael
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: The Journal of Haemophilia Practice, Vol 9, Iss 1, Pp 147-155 (2023)
Druh dokumentu: article
ISSN: 2055-3390
DOI: 10.2478/jhp-2022-0020
Popis: Haemophilia A and B are X-linked inherited bleeding disorders, resulting in the deficiency of clotting factor VIII and IX, respectively. Since the introduction of recombinant clotting factor concentrates in the early 1990s, the major safety concern for haemophilia therapy has been the development of inhibitory antibodies, or inhibitors. Over the recent past, new therapies for the treatment and prevention of bleeding have received regulatory approval or are under study.
Databáze: Directory of Open Access Journals